Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.4
USERS' SCORE
Good
Based on 3 Reviews
8.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B6 (as Pyridoxal-5-Phosphate)
1.5 mg
88%
Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt])
680 mcg DFE‡
170%
Vitamin B12 (as Methylcobalamin)
1,000 mcg
41,667%

Top Medical Research Studies

9.5
Vitamin B1 shows promising results
We assessed how effective oral vitamin B1 could be in treating primary dysmenorrhea, which causes significant pelvic pain in young women. In a robust study involving 556 participants aged 12-21 years, we administered 100 mg of vitamin B1 daily for 90 days.

The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
Read More
We analyzed various treatments for heavy menstrual bleeding and pain linked to intrauterine device (IUD) use, focusing on randomized controlled trials.

Among the 21 trials we reviewed, we found that vitamin B1 helped reduce bleeding days for Cu IUD users. However, most evidence was weak and uncertain, especially regarding other treatments like naproxen and tranexamic acid, which didn’t show clear benefits.

Overall, more robust studies are essential to confirm these findings and explore vitamin B's role further.
Read More
We looked into how a combination of mannitol and B vitamins could help manage pelvic pain caused by piriformis syndrome. In our study, 22 patients received a five-day intravenous infusion of mannitol and a six-week course of B vitamins.

After treatment, significant improvements were noted in tenderness and pain levels, assessed by various clinical tests and scales. Patients reported less discomfort during rest, activities, and long sitting. Overall, the results suggest that this approach could be an effective alternative for managing piriformis syndrome.
Read More

Most Useful Reviews

9
Numbness alleviated
7 people found this helpful
I developed a straight neck from poor posture, leading to shoulder blade pain, cervical hernia, and carpal tunnel syndrome, with persistent numbness for two months. I considered surgery but opted for vitamin B12 after extensive research. It doesn’t work instantly, but after a week, the numbness began to subside, and soon disappeared. I feel much better now. If you experience similar symptoms, I strongly recommend this supplement.
Read More
7.5
Reduced joint pain
15 people found this helpful
The endocrinologist prescribed this supplement for elevated homocysteine and disturbed folate cycle. The vitamins are tasty and taken sublingually. Unexpectedly, my joint pain, especially in my back due to a lumbar hernia, has significantly decreased. I learned that B vitamins can alleviate joint pain. Moreover, I've fallen ill less frequently. Consequently, I purchased it for my grandson as well. They truly work!
Read More
0
Headaches experienced
The drug did not suit me. I began to experience headaches upon taking it. Once I stopped, the pain ceased.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.4
  • All Researches
9.5
Vitamin B1 shows promising results
We assessed how effective oral vitamin B1 could be in treating primary dysmenorrhea, which causes significant pelvic pain in young women. In a robust study involving 556 participants aged 12-21 years, we administered 100 mg of vitamin B1 daily for 90 days.

The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
Read More
We looked into how a combination of mannitol and B vitamins could help manage pelvic pain caused by piriformis syndrome. In our study, 22 patients received a five-day intravenous infusion of mannitol and a six-week course of B vitamins.

After treatment, significant improvements were noted in tenderness and pain levels, assessed by various clinical tests and scales. Patients reported less discomfort during rest, activities, and long sitting. Overall, the results suggest that this approach could be an effective alternative for managing piriformis syndrome.
Read More
8
Vitamin B1 showed promise for dysmenorrhea
We explored the effects of vitamin B1 and fish oil on dysmenorrhea in high school students. Conducting a double-blind clinical trial, we observed 240 female students divided into four groups, receiving vitamin B1, fish oil, both, or a placebo over two months.

The results showed that vitamin B1 and fish oil were similarly effective, but vitamin B1 had fewer complications and was better tolerated. Notably, the combination of vitamin B1 and fish oil provided the greatest relief from pain duration compared to the other groups.
Read More
We analyzed various treatments for heavy menstrual bleeding and pain linked to intrauterine device (IUD) use, focusing on randomized controlled trials.

Among the 21 trials we reviewed, we found that vitamin B1 helped reduce bleeding days for Cu IUD users. However, most evidence was weak and uncertain, especially regarding other treatments like naproxen and tranexamic acid, which didn’t show clear benefits.

Overall, more robust studies are essential to confirm these findings and explore vitamin B's role further.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Numbness alleviated
7 people found this helpful
I developed a straight neck from poor posture, leading to shoulder blade pain, cervical hernia, and carpal tunnel syndrome, with persistent numbness for two months. I considered surgery but opted for vitamin B12 after extensive research. It doesn’t work instantly, but after a week, the numbness began to subside, and soon disappeared. I feel much better now. If you experience similar symptoms, I strongly recommend this supplement.
Read More
7.5
Reduced joint pain
15 people found this helpful
The endocrinologist prescribed this supplement for elevated homocysteine and disturbed folate cycle. The vitamins are tasty and taken sublingually. Unexpectedly, my joint pain, especially in my back due to a lumbar hernia, has significantly decreased. I learned that B vitamins can alleviate joint pain. Moreover, I've fallen ill less frequently. Consequently, I purchased it for my grandson as well. They truly work!
Read More
0
Headaches experienced
The drug did not suit me. I began to experience headaches upon taking it. Once I stopped, the pain ceased.
Read More

Frequently Asked Questions

9
Numbness alleviated
7 people found this helpful
I developed a straight neck from poor posture, leading to shoulder blade pain, cervical hernia, and carpal tunnel syndrome, with persistent numbness for two months. I considered surgery but opted for vitamin B12 after extensive research. It doesn’t work instantly, but after a week, the numbness began to subside, and soon disappeared. I feel much better now. If you experience similar symptoms, I strongly recommend this supplement.
7.5
Reduced joint pain
15 people found this helpful
The endocrinologist prescribed this supplement for elevated homocysteine and disturbed folate cycle. The vitamins are tasty and taken sublingually. Unexpectedly, my joint pain, especially in my back due to a lumbar hernia, has significantly decreased. I learned that B vitamins can alleviate joint pain. Moreover, I've fallen ill less frequently. Consequently, I purchased it for my grandson as well. They truly work!
0
Headaches experienced
The drug did not suit me. I began to experience headaches upon taking it. Once I stopped, the pain ceased.
9.5
Vitamin B1 shows promising results
We assessed how effective oral vitamin B1 could be in treating primary dysmenorrhea, which causes significant pelvic pain in young women. In a robust study involving 556 participants aged 12-21 years, we administered 100 mg of vitamin B1 daily for 90 days.

The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
We looked into how a combination of mannitol and B vitamins could help manage pelvic pain caused by piriformis syndrome. In our study, 22 patients received a five-day intravenous infusion of mannitol and a six-week course of B vitamins.

After treatment, significant improvements were noted in tenderness and pain levels, assessed by various clinical tests and scales. Patients reported less discomfort during rest, activities, and long sitting. Overall, the results suggest that this approach could be an effective alternative for managing piriformis syndrome.

References

  1. Christelle K, Norhayati MN, Jaafar SH. Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine-device use. Cochrane Database Syst Rev. 2022;8:CD006034. 10.1002/14651858.CD006034.pub3
  2. Huang ZF, Lin BQ, Torsha TT, Dilshad S, Yang DS, et al. Effect of Mannitol plus Vitamins B in the management of patients with piriformis syndrome. J Back Musculoskelet Rehabil. 2019;32:329. 10.3233/BMR-170983
  3. Hosseinlou A, Alinejad V, Alinejad M, Aghakhani N. The effects of fish oil capsules and vitamin B1 tablets on duration and severity of dysmenorrhea in students of high school in Urmia-Iran. Glob J Health Sci. 2014;6:124. 10.5539/gjhs.v6n7p124
  4. Gokhale LB. Curative treatment of primary (spasmodic) dysmenorrhoea. Indian J Med Res. 1996;103:227.
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